Temperature-Programmed Gas Chromatography

PART I: Introduction

BASIC CONCEPTS AND TERMS A COLUMN Retention Mechanisms Structures Operational Modes Specific and General Properties of a Column Boundaries

PART II: Background

LINEAR SYSTEMS Problem Review: Metrics for Peak Retention Time and Width Chromatograph as an Information Processing System Properties of Linear Systems Mathematical Moments of Functions Properties of Mathematical Moments Pulses

MIGRATION OF A SOLID OBJECT Velocity of an Object Parameters of Migration Path Relations between Path Parameters and Object Parameters

SOLUTE-LIQUID INTERACTION IN GAS CHROMATOGRAPHY Distribution Constant and Retention Factor Chromatographic Parameters of Solute-Liquid Interaction Alternative Expressions of Ideal Retention Model Linearized Retention Model Relations between Characteristics Parameters Appendix. Relative Errors in Power Functions

MOLECULAR PROPERTIES OF IDEAL GAS Theory Gas Viscosity and Related Parameters ? Empirical Formulae Empirical Formulae for Solute Diffusity in a Gas Appendix

FLOW OF IDEAL GAS Mass-Conserving Flow Pneumatic Parameters Relations between Pneumatic Parameters Appendix

PART III: Formation of Chromatogram

FORMATION OF RETENTION TIMES Solute Mobility Solute-Column Interaction and Solute Migration General Equations of a Solute Migration and Elution Uniform Solute Mobility in Isobaric Analysis Scalability of Retention Times in Isobaric Analyses Dimensionless Parameters Boundaries of Linearized Model Appendix

FORMATION OF PEAK SPACING Static GC Analysis Closely Migrating Solutes in Dynamic Analysis Isobaric Linear Heating Ramp and Highly Interactive Solutes Properties of Generic Solutes Appendix. Elution Temperature Interval

FORMATION OF PEAK WIDTHS Overview Local Plate Height Solute Zone in Non-Uniform Medium Apparent Plate Number and Height Thin Film Columns Thick Film Columns Temperature-Programmed Analyses Temperature-Programmed Thin Film Columns Packed Columns Scalability of Peak Widths in

Dr. Leonid M. Blumberg obtained his academic degrees in electrical engineering and training in mathematics from leading institutions of higher education in St. Petersburg. In 1977, Dr. Blumberg immigrated to USA and joined Hewlett-Packard Co. where he became a theoretician responsible for the definition of new GC instruments and the optimization of GC analyses.

After leaving HP in 1998, Dr. Blumberg continued the development of theoretical foundation for optimization of conventional, fast and multidimensional GC where he is a world leading expert. Dr. Blumberg authored 45 scientific publications and patented 19 inventions.

"It best serves as a reference book on GC theory and, at that, it probably is the best one out there. I expect I will continue to use this book for many, many years to come and I recommend it to anyone using GC for anything more than the simplest of purposes." ( Journal of Chemical Education , 18 November 2012)