The Serpin Family
Proteins with Multiple Functions in Health and Disease
(Sprache: Englisch)
The book provides an comprehensive overview on biology, genetics and cellular functions of serpins (serine protease inhibitors) in health and disease. With over 1000 members serpins are the most diverse family of protease inhibitors. Latest groundbreaking...
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Klappentext zu „The Serpin Family “
The book provides an comprehensive overview on biology, genetics and cellular functions of serpins (serine protease inhibitors) in health and disease. With over 1000 members serpins are the most diverse family of protease inhibitors. Latest groundbreaking research findings are presented and broaden the understanding on inhibitory and non-inhibitory serpins, not only in mammalian organisms but also in insects, worms, plants and viruses.
Inhaltsverzeichnis zu „The Serpin Family “
1. Serpin Evolution and Genetics2. Serpin Structure and Mechanism
3. New Serpins / New Functions of Serpins in Coagulation, Fibrinolysis, and Angiogenesis
4. Serpins in Development and Reproduction
5. Intracellular clade B serpins, intracellular functions of other serpins
6. Interaction of Serpins with Membrane-anchored Proteases
7. Serpins in Neurobiology
8. Serpins in Inflammation and Infectious Diseases
9. Cellular Proteostasis Systems Responsible for Orchestrating SERPIN Conformational Maturation and/or Disposal
10. SERPIN-related Diseases: Cellular Injury, Disease Modifiers, and Therapeutic Approaches
11. Serpins in Cancer
12. Non-mammalian Serpins
13. Serpins and Signal Transduction
14. Non-inhibitory serpins: structures and functions
15. (Patho)-physiology and/or novel functions of human serpins (in particular: vaspin) Serpins in animal models
Autoren-Porträt
Univ. Prof. Dr. Margarethe Geiger Department of Vascular Biology and Thrombosis Research, Center of Physiology and Pharmacology, Medical University of Vienna, Schwarzspanierstrasse 17, 1090 Wien Margarethe Geiger is a professor of vascular physiology at the Medical University of Vienna. Her research is focused on the role of non-inhibitory serine protease inhibitors in cell signaling. Dr. Margareta Furtmüller Department of Vascular Biology and Thrombosis Research, Med. Univ. Vienna, Schwarzspanierstrasse 17, 1090 Wien, email: margareta.furtmueller@meduniwien.ac.at Dr. Felix Wahlmüller Department of Vascular Biology and Thrombosis Research, Med. Univ. Vienna, Schwarzspanierstrasse 17, 1090 Wien, email: felix.wahlmueller@meduniwien.ac.at
Bibliographische Angaben
- 2015, 1st ed. 2015, VIII, 329 Seiten, Maße: 16 x 24,1 cm, Gebunden, Englisch
- Herausgegeben: Margarethe Geiger, Felix Wahlmüller, Margareta Furtmüller
- Verlag: Springer, Berlin
- ISBN-10: 3319227106
- ISBN-13: 9783319227108
- Erscheinungsdatum: 25.11.2015
Sprache:
Englisch
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