Transplantation at a Glance

Preface 7
 
List of abbreviations 8
 
1 History of transplantation 10
 
Organ donors
 
2 Diagnosis of death and its physiology 12
 
3 Deceased organ donation 14
 
4 Live donor kidney transplantation 16
 
5 Live donor liver transplantation 18
 
Organ preservation
 
6 Organ preservation 20
 
Immunology of organ transplantation
 
7 Innate immunity 22
 
8 Adaptive immunity and antigen presentation 24
 
9 Humoral and cellular immunity 26
 
Histocompatibility in transplantation
 
10 Tissue typing and HLA matching 28
 
11 Detecting HLA antibodies 30
 
12 Antibody-incompatible transplantation 32
 
Organ allocation
 
13 Organ allocation 34
 
Immunosuppression
 
14 Immunosuppression: induction vs maintenance 36
 
15 Biological agents 37
 
16 T cell-targeted immunosuppression 38
 
Complications of immunosuppression
 
17 Side effects of immunosuppressive agents 40
 
18 Post-transplant infection 42
 
19 CMV infection 44
 
20 Post-transplant malignancy 46
 
Kidney transplantation
 
21 End-stage renal failure 48
 
22 Complications of ESRF 50
 
23 Dialysis and its complications 52
 
24 Assessment for kidney transplantion 54
 
25 Kidney transplantation: the operation 56
 
26 Surgical complications of kidney transplantation 58
 
27 Delayed graft function 60
 
28 Transplant rejection 62
 
29 Chronic renal allograft dysfunction 64
 
Pancreas and islet transplantation
 
30 Transplantation for diabetes mellitus 66
 
31 Pancreas transplantation 68
 
32 Islet transplantation 70
 
Liver transplantation
 
33 Causes of liver failure 72
 
34 Assessment for liver transplantation 74
 
35 Liver transplantation: the operation 76
 
36 Complications of liver transplantation

Menna Clatworthy is at the University of Cambridge and Addenbrooke's Hospital
 
Christopher Watson is at the School of Clinical Medicine, University of Cambridge
 
Michael Allison is at Cambridge University Hospitals NHS Foundation Trust
 
John Dark is Professor of Cardiothoracic Surgery at the Regional Cardiothoracic Centre, The Freeman Hospital, Newcastle upon Tyne

"This is one of the best reviews of transplantation I have had the pleasure of reading. With its thorough collection of topics and its illustrations, it is a definite must read for those who are starting their training or spending a limited amount of time on a transplant service." ("Doody's", 19 April 2013)

"This is one of the best reviews of transplantation I have had the pleasure of reading. With its thorough collection of topics and its illustrations, it is a definite must read for those who are starting their training or spending a limited amount of time on a transplant service." (Doody's, 19 April 2013)
This is a superbly produced small book with marvellous illustrations, and I am literally amazed how much information is presented in approximately 100 pages. The illustrations have been very carefully done and enhance the explanations in the text extremely well. The chapters range from a history of transplantation through organ donation and preservation; the immunology of organ transplantation; immunosuppression; complications of immunosuppression, and kidney, pancreas, liver, intestinal, and lung transplantations, finishing up with brief reviews of composite tissue transplantation and xenotransplantation.
This is the ideal book to give to nurses or residents rotating through a transplantation unit or to scientists working in tissue typing or microbiology and virology with an interest in transplantation. Obviously, for those who stay in the field, they will need more in-depth information from the larger texts, but as a starter book, I have seen nothing better than this extremely good presentation. Each transplantation unit should have half a dozen or so available for those I have referred to above. (Peter J. Morris , Transplantation journal, 2012)