Wound Regeneration and Repair
Methods and Protocols
(Sprache: Englisch)
This book details classical and cutting-edge methods for studying wound healing and regeneration. It includes a detailed list of the necessary materials and reagents for each procedure and step-by-step, reproducible laboratory protocols.
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Produktinformationen zu „Wound Regeneration and Repair “
This book details classical and cutting-edge methods for studying wound healing and regeneration. It includes a detailed list of the necessary materials and reagents for each procedure and step-by-step, reproducible laboratory protocols.
Klappentext zu „Wound Regeneration and Repair “
In Wound Regeneration and Repair: Methods and Protocols, expert researchers in the field detail classical and cutting-edge methods for studying wound healing and regeneration. These techniques include cellular and molecular methods, genetic approaches, surgical procedures, clinical advances, drug discovery and delivery modalities, animal and humanized models and new applications in the treatment of pathological wounds in a variety of organs and tissues. Written in the highly successful Methods in Molecular Biology series format, chapters include an introduction to their respective topics, a detailed list of the necessary materials and reagents for each procedure, step-by-step, reproducible laboratory protocols, and a set notes, developed by the authors, for troubleshooting and avoiding known pitfalls.Authoritative and practical, Wound Regeneration and Repair: Methods and Protocols seeks to aid scientists and entrepreneurs in their further study of technologies, models, techniques, and critical new areas and approaches to clinical and commercial translation of research.
Inhaltsverzeichnis zu „Wound Regeneration and Repair “
Part I: Tissue Engineered Wound Repair Models1. An In Vivo Model System for Evaluation of the Host Response to Biomaterials
Brian Sicari, Neill Turner, and Stephen Badylak
2. Urothelial Cell Culture
Yuanyuan Zhang and Anthony Atala
3. Cell Populated Collagen Lattices Contraction Model for the
Investigation of Fibroblast Collagen Interactions
H Paul Ehrlich, and Kurtis E Moyer,
4. A Tissue-engineered Corneal Wound Healing Model for the Characterization of Reepithelialization
Karine Zaniolo, Patrick Carrier, Sylvain L. Guérin, François A. Auger and Lucie Germain
Part II: Stem Cells and Would Repair
5. Adult Stem Cells in Small Animal Wound Healing Models
Nauta, Allison C., Gurtner, Geoffrey C., Longaker, and Michael T.,
6. Novel Animal Models for Tracking the Fate and Contributions of Bone Marrow Derived Cells in Diabetic Healing
Robert C. Caskey and Kenneth W. Liechty
7.
8. Cell-Based Therapies for Myocardial Repair: Emerging Role for Bone Marrow Derived Mesencymal Stem Cells (MSCs) in the Treatment of the Chronically Injured Heart
Jose S. Da Silva and Joshua M. Hare
9. A Model System for Primary Abdominal Closures
Michael J. Yost, Mary O. Morales, Veronica Rodriguez-Rivera, Eric M. Yost, Louis Terracio and Stephen A. Fann
Part III: Skin and Corneal Wound Repair Models
10. Alternatives for Animal Wound Model Systems
Phil Stephens, Matthew Caley, and Matthew Peake
11. Novel Methods for the Investigation of Human Hypertrophic Scarring
... mehr
and other Dermal Fibrosis
Dariush Honardoust, Peter Kwan, Moein Momtazi, Jie Ding , and Edward E Tredget
12. Study of the Human Chronic Wound Tissue: Addressing Logistic Barriers and Productive use of Laser Capture Microdissection
Sashwati Roy and Chandan K Sen
13. The Wound Watch: An Objective Staging System for Wounds in the Diabetic (db/db) Mouse Model
G. Pietramaggiori, , S. Scherer, and DP. Orgill,
14. Human Ex vivo Wound Healing Model
Stojadinovic Olivera and Marjana Tomic - Canic
15. Murine Models of Human Wound Healing
Jerry S. Chen, Michael T. Longaker, and Geoffrey C. Gurtner
Part IV: Cardiovascular Wound Healing Models
16. A Corneal Scarring Model
Daniel J. Gibson and Gregory S. Schultz
17. A Novel and Efficient Model of Coronary Artery Ligation in the Mouse
Erhe Gao and Walter J. Koch
18. Cardiac Wound Healing Post-Myocardial Infarction: A Novel Method to Target Extracellular Matrix Remodeling in the Left Ventricle
Rogelio Zamilpa, Jianhua Zhang, Ying Ann Chiao, Lisandra de Castro Bras, Ganesh Halade, Yonggang Ma, Sander O. Hacker, and Merry L. Lindsey
19. Injury Models to Study Cardiac Remodeling in the Mouse: Myocardial Infarction and Ischemia-reperfusion
Daniel J. Luther, Charles K. Thodeti, and J. Gary Meszaros
20. Cryoinjury Models of the Adult and Neonatal Mouse Heart for Studies of Scarring and Regeneration
Erik G. Strungs, Emily L. Ongstad, Michael P. O'Quinn, Joseph A. Palatinus, L. Jane Jourdan, and Robert G. Gourdie
21. Targeting Wnt Signaling to Improve Wound Healing after Myocardial Infarction
Evangelos P. Daskalopoulos, Ben J.A. Janssen and W. Matthijs Blankesteijn
22. Vascular Connexins in Restenosis after Balloon Injury
Sandrine Morel and Brenda R. Kwak
Part V: Non Mammalian and Mammalian Models of Regenerative Repair
23. Gain-of-function Assays in the Axolotl (Ambystoma mexicanum) to Identify Signaling Pathways that Induce and Regulate Limb Regeneration
Jangwoo Lee, Cristian Aguilar and David Gardiner
24. The Mouse Digit Tip: from Wound Healing to Regeneration
Jennifer Simkin, Manjong Han, Ling Yu, Mingquan Yan, and Ken Muneoka 25. Lower Vibrissa Follicle Amputation: A Mammalian Model of RegenerationJames M. Waters and Allison J. Cowin
26. Using Drosophila Larvae to Study Epidermal Wound Closure and Inflammation
Sirisha Burra, Yan Wang, Amanda R. Brock, and Michael J. Galko
27. Zebrafish Cardiac Injury and Regeneration Models: A Non-invasive and Invasive in vivo Model of Cardiac Regeneration
Michael S. Dickover, Ruilin Zhang, Peidong Han, and Neil C. Chi
Part VI: Wound Healing Cell Biology
28. Quantifying Alterations in Cell Migration: Tracking Fluorescently Tagged Migrating Cells by FACs and Live Imaging
Rachael Z. Murray
29. Examining the Role of Mast Cells in Fetal Wound Healing using Cultured Cells in vitro
Brian C. Wulff and Traci A. Wilgus
30. Assessing Macrophage Phenotype During Tissue Repair
Timothy J. Koh, Margaret L. Novak, and Rita E. Mirza
31. The use of Connexin-Based Therapeutic Approaches to Target Inflammatory Diseases
Simon J O'Carroll, David L Becker, Joanne O Davidson, Alistair J Gunn, Louise FB Nicholson, and Colin R Green
Part VII: Commercialization of Wound Repair and Regenerative Discoveries
32. Commercialization: Patenting and Licensing in Wound Healing and Regenerative Biology
W.Chip. Hood and David Huizenga
33. Translational Strategies for the Development of a Wound Healing Technology (idea) from Bench to Bedside
Gautam S. Ghatnekar and Tuan A. Elstrom
Dariush Honardoust, Peter Kwan, Moein Momtazi, Jie Ding , and Edward E Tredget
12. Study of the Human Chronic Wound Tissue: Addressing Logistic Barriers and Productive use of Laser Capture Microdissection
Sashwati Roy and Chandan K Sen
13. The Wound Watch: An Objective Staging System for Wounds in the Diabetic (db/db) Mouse Model
G. Pietramaggiori, , S. Scherer, and DP. Orgill,
14. Human Ex vivo Wound Healing Model
Stojadinovic Olivera and Marjana Tomic - Canic
15. Murine Models of Human Wound Healing
Jerry S. Chen, Michael T. Longaker, and Geoffrey C. Gurtner
Part IV: Cardiovascular Wound Healing Models
16. A Corneal Scarring Model
Daniel J. Gibson and Gregory S. Schultz
17. A Novel and Efficient Model of Coronary Artery Ligation in the Mouse
Erhe Gao and Walter J. Koch
18. Cardiac Wound Healing Post-Myocardial Infarction: A Novel Method to Target Extracellular Matrix Remodeling in the Left Ventricle
Rogelio Zamilpa, Jianhua Zhang, Ying Ann Chiao, Lisandra de Castro Bras, Ganesh Halade, Yonggang Ma, Sander O. Hacker, and Merry L. Lindsey
19. Injury Models to Study Cardiac Remodeling in the Mouse: Myocardial Infarction and Ischemia-reperfusion
Daniel J. Luther, Charles K. Thodeti, and J. Gary Meszaros
20. Cryoinjury Models of the Adult and Neonatal Mouse Heart for Studies of Scarring and Regeneration
Erik G. Strungs, Emily L. Ongstad, Michael P. O'Quinn, Joseph A. Palatinus, L. Jane Jourdan, and Robert G. Gourdie
21. Targeting Wnt Signaling to Improve Wound Healing after Myocardial Infarction
Evangelos P. Daskalopoulos, Ben J.A. Janssen and W. Matthijs Blankesteijn
22. Vascular Connexins in Restenosis after Balloon Injury
Sandrine Morel and Brenda R. Kwak
Part V: Non Mammalian and Mammalian Models of Regenerative Repair
23. Gain-of-function Assays in the Axolotl (Ambystoma mexicanum) to Identify Signaling Pathways that Induce and Regulate Limb Regeneration
Jangwoo Lee, Cristian Aguilar and David Gardiner
24. The Mouse Digit Tip: from Wound Healing to Regeneration
Jennifer Simkin, Manjong Han, Ling Yu, Mingquan Yan, and Ken Muneoka 25. Lower Vibrissa Follicle Amputation: A Mammalian Model of RegenerationJames M. Waters and Allison J. Cowin
26. Using Drosophila Larvae to Study Epidermal Wound Closure and Inflammation
Sirisha Burra, Yan Wang, Amanda R. Brock, and Michael J. Galko
27. Zebrafish Cardiac Injury and Regeneration Models: A Non-invasive and Invasive in vivo Model of Cardiac Regeneration
Michael S. Dickover, Ruilin Zhang, Peidong Han, and Neil C. Chi
Part VI: Wound Healing Cell Biology
28. Quantifying Alterations in Cell Migration: Tracking Fluorescently Tagged Migrating Cells by FACs and Live Imaging
Rachael Z. Murray
29. Examining the Role of Mast Cells in Fetal Wound Healing using Cultured Cells in vitro
Brian C. Wulff and Traci A. Wilgus
30. Assessing Macrophage Phenotype During Tissue Repair
Timothy J. Koh, Margaret L. Novak, and Rita E. Mirza
31. The use of Connexin-Based Therapeutic Approaches to Target Inflammatory Diseases
Simon J O'Carroll, David L Becker, Joanne O Davidson, Alistair J Gunn, Louise FB Nicholson, and Colin R Green
Part VII: Commercialization of Wound Repair and Regenerative Discoveries
32. Commercialization: Patenting and Licensing in Wound Healing and Regenerative Biology
W.Chip. Hood and David Huizenga
33. Translational Strategies for the Development of a Wound Healing Technology (idea) from Bench to Bedside
Gautam S. Ghatnekar and Tuan A. Elstrom
... weniger
Bibliographische Angaben
- 2013, 2013, XVIII, 585 Seiten, 102 farbige Abbildungen, Maße: 18,3 x 26 cm, Gebunden, Englisch
- Herausgegeben: Robert G. Gourdie, Tereance A. Myers
- Verlag: Springer, Berlin
- ISBN-10: 1627035044
- ISBN-13: 9781627035040
- Erscheinungsdatum: 13.09.2013
Sprache:
Englisch
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