Lipid Rafts and Caveolae (PDF)
From Membrane Biophysics to Cell Biology
(Sprache: Englisch)
This keenly awaited first overview of the field represents a complete guide to the structure and function of the most important mammalian cell membrane organelles. Filling a huge gap in the primary literature, this book is the first to cover the subject in...
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Produktinformationen zu „Lipid Rafts and Caveolae (PDF)“
This keenly awaited first overview of the field represents a complete guide to the structure and function of the most important mammalian cell membrane organelles. Filling a huge gap in the primary literature, this book is the first to cover the subject in detail.
Following an introduction by Kai Simons, the discoverer of lipid rafts and the most prominent scientist in the field, chapters include:
Historical background
Distinct structures and functions
Structural basis
Signaling
Viral entry and virion budding
Cholesterol transport
Caveolins
Lipid shells
Cell polarity and intracellular trafficking
Cancer cells
Of prime importance to molecular and cell biologists, biochemists, membrane scientists, cancer researchers, and virologists.
Following an introduction by Kai Simons, the discoverer of lipid rafts and the most prominent scientist in the field, chapters include:
Historical background
Distinct structures and functions
Structural basis
Signaling
Viral entry and virion budding
Cholesterol transport
Caveolins
Lipid shells
Cell polarity and intracellular trafficking
Cancer cells
Of prime importance to molecular and cell biologists, biochemists, membrane scientists, cancer researchers, and virologists.
Inhaltsverzeichnis zu „Lipid Rafts and Caveolae (PDF)“
Lipid Rafts, Caveolae, and Membrane Traffic The Forces that Shape Caveolae The Biophysical Characterization of Lipid Rafts The Role of Caveolae and Noncaveolar Rafts in Endocytosis Role of Cholesterol in Signal Transduction from Caveolae Phosphorylation of Caveolin and Signaling from Caveolae Role of Lipid Microdomains in the Formation of Supramolecular Protein Complexes and Transmembrane Signaling Caveolin and its Role in Intracellular Chaperone Complexes The Roles of Caveolae and Caveolin in Cell Shape, Locomotion, and Stress Fiber Formation Lipid Rafts in Trafficking and Processing of Prion Protein and Amyloid Precursor Protein Caveolae and the Endothelial Nitric Oxide Synthase The Role of Caveolin-1 in Tumor Cell Survival and Cancer Progression
Autoren-Porträt
Christopher Fielding is Neider Professor of Cardiovascular Physiology at the University of California at San Francisco (UCSF). He graduated from University College in London (UK) where he also received his PhD. After appointments at Oxford University and at the University of Chicago, he joined the faculty at UCSF in 1971, being appointed full professor in 1985.Professor Fielding's main research interest is in the trafficking of cholesterol, its regulation and its role in signal transduction.
Bibliographische Angaben
- 2006, 1. Auflage, 278 Seiten, Englisch
- Herausgegeben: Christopher J. Fielding
- Verlag: Wiley-VCH
- ISBN-10: 3527607501
- ISBN-13: 9783527607501
- Erscheinungsdatum: 13.12.2006
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- Größe: 11 MB
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Sprache:
Englisch
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