Metabotropic GPCRs: TGR5 and P2Y Receptors in Health and Diseases (PDF)
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This book will provide current understandings about two ubiquitously expressed metabotropic GPCRs, G-coupled purinoreceptor type 2 (P2Y) and Takeda G-protein-coupled bile acid receptor 5 (TGR5). G protein coupled receptors (GPCRs) are the largest family of proteins implicated in majority of cellular responses. The two receptor sub-families play a central role in many physiological functions as well as in many pathological conditions. This book offers up-to-date information on the physiological functions, signaling pathways and regulatory mechanisms of P2Y and TGR5 receptors. In addition, this book provides a comprehensive overview about the abnormalities of P2Y/TGR5 receptors and their contribution in the development and progression of pathological conditions. It also covers the currently available natural, chemical and pharmacological agents targeting these two receptor families and their therapeutic implications in P2Y and TGR5 associated disorders. This book is a valuable source for beginners and researchers to follow the rapidly progressing field of these two GPCR subfamily members.
He has published nearly 48 research articles in various peer-reviewed international journals, 18 book chapters, and presented a research articles in number of conferences, proceedings and attended various workshops/seminars. He is on the editorial/reviewer board in many peer-reviewed international journals such as Frontiers in Cellular Neuroscience, American Journal of Biochemistry and Molecular Biology, Neuroscience, etc. He is member of various prestigious scientific associations like Indian Society for Atherosclerosis Research (ISAR), The International Science Congress Association (ISCA), Society of Biological Chemistry (SBC), Society for Free Radical Research India (SFRR), The Indian Society of Cell Biology (ISCB) and member of American Association of Pharmaceutical Scientists (AAPS) and Science Advisory Board (SAB).
Dr. Murugavel Ponnusamy is presently working as Postdoctoral Research Associate at the Center for Developmental Cardiology,
- Autoren: Senthilkumar Rajagopal , Murugavel Ponnusamy
- 2018, 1st ed. 2018, 76 Seiten, Englisch
- Verlag: Springer-Verlag GmbH
- ISBN-10: 981131571X
- ISBN-13: 9789811315718
- Erscheinungsdatum: 19.11.2018
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- Größe: 2.92 MB
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