Organometallic Chemistry in Industry (PDF)
A Practical Approach
(Sprache: Englisch)
Showcases the important role of organometallic chemistry in industrial applications and includes practical examples and case studies
This comprehensive book takes a practical approach to how organometallic chemistry is being used in industrial...
This comprehensive book takes a practical approach to how organometallic chemistry is being used in industrial...
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Showcases the important role of organometallic chemistry in industrial applications and includes practical examples and case studies
This comprehensive book takes a practical approach to how organometallic chemistry is being used in industrial applications. It uniquely offers numerous, real-world examples and case studies that aid working R&D researchers as well as Ph.D. and postdoc students preparing to ace interviews in order to enter the workforce. Edited by two world-leading and established industrial chemists, the book covers flow chemistry (catalytic and non-catalytic organometallic chemistry), various cross-coupling reactions (C-C, C-N, and C-B) in classical batch chemistry, conjugate addition reactions, metathesis, and C-H arylation and achiral hydrogenation reactions.
Beginning with an overview of the many industrial milestones within the field over the years, Organometallic Chemistry in Industry: A Practical Approach provides chapters covering: the design, development, and execution of a continuous flow enabled API manufacturing route; continuous manufacturing as an enabling technology for low temperature organometallic chemistry; the development of a nickel-catalyzed enantioselective Mizoroki-Heck coupling; and the development of iron-catalyzed Kumada cross-coupling for the large scale production of Aliskiren intermediates. The book also examines aspects of homogeneous hydrogenation from industrial research; the latest industrial uses of olefin metathesis; and more.
-Includes rare industrial case studies difficult to find in current literature
-Helps readers successfully carry out their own reactions
-Covers topics like flow chemistry, cross-coupling reactions, and dehydrative decarbonylation
-Features a foreword by Nobel Laureate R. H. Grubbs
-A perfect resource for every R&D researcher in industry
-Useful for PhD students and postdocs: excellent preparation for a job interview
Organometallic Chemistry in Industry: A Practical Approach is an excellent resource for all chemists, including those working in the pharmaceutical industry and organometallics.
This comprehensive book takes a practical approach to how organometallic chemistry is being used in industrial applications. It uniquely offers numerous, real-world examples and case studies that aid working R&D researchers as well as Ph.D. and postdoc students preparing to ace interviews in order to enter the workforce. Edited by two world-leading and established industrial chemists, the book covers flow chemistry (catalytic and non-catalytic organometallic chemistry), various cross-coupling reactions (C-C, C-N, and C-B) in classical batch chemistry, conjugate addition reactions, metathesis, and C-H arylation and achiral hydrogenation reactions.
Beginning with an overview of the many industrial milestones within the field over the years, Organometallic Chemistry in Industry: A Practical Approach provides chapters covering: the design, development, and execution of a continuous flow enabled API manufacturing route; continuous manufacturing as an enabling technology for low temperature organometallic chemistry; the development of a nickel-catalyzed enantioselective Mizoroki-Heck coupling; and the development of iron-catalyzed Kumada cross-coupling for the large scale production of Aliskiren intermediates. The book also examines aspects of homogeneous hydrogenation from industrial research; the latest industrial uses of olefin metathesis; and more.
-Includes rare industrial case studies difficult to find in current literature
-Helps readers successfully carry out their own reactions
-Covers topics like flow chemistry, cross-coupling reactions, and dehydrative decarbonylation
-Features a foreword by Nobel Laureate R. H. Grubbs
-A perfect resource for every R&D researcher in industry
-Useful for PhD students and postdocs: excellent preparation for a job interview
Organometallic Chemistry in Industry: A Practical Approach is an excellent resource for all chemists, including those working in the pharmaceutical industry and organometallics.
Autoren-Porträt
Thomas J. Colacot is R&D Fellow, and Director of Global Technology Innovation (Lab and Specialty Chemicals) at Millipore Sigma, USA. His expertise is in the areas of new product and technology development, process R&D, scale-up, tech transfers of organic, organometallic and fine chemicals relevant for pharmaceutical, electronic, and biological applications with very strong interactions/partnership with customers. He is one of the outstanding scientists featured by Merck: https://www.merckgroup.com/en/research/science-space/scientists/thomas-colacot.html Carin Johansson Seechurn is researcher in the Catalysis and Chiral Technologies division of Johnson Matthey in Royston, UK, where she is working on the development and scale-up of novel homogeneous metal catalysts.
Bibliographische Angaben
- 2020, 1. Auflage, 316 Seiten, Englisch
- Herausgegeben: Thomas Colacot, Carin Johansson Seechurn
- Verlag: Wiley-VCH GmbH
- ISBN-10: 3527819177
- ISBN-13: 9783527819171
- Erscheinungsdatum: 11.02.2020
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- Größe: 13 MB
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Englisch
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