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Protein Instability at Interfaces During Drug Product Development / AAPS Advances in the Pharmaceutical Sciences Series Bd.43 (PDF)

Fundamental Understanding, Evaluation, and Mitigation (Sprache: Englisch)
 
 
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Proteins are exposed to various interfacial stresses during drug product development. They are subjected to air-liquid, liquid-solid, and, sometimes, liquid-liquid interfaces throughout the development cycle-from manufacturing of drug substances to storage...
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