Protein Quality Control in Neurodegenerative Diseases / Research and Perspectives in Alzheimer's Disease (PDF)
(Sprache: Englisch)
The health of the proteome depends upon protein quality control to regulate the proper synthesis, folding., translocation, and clearance of proteins. The cell is challenged constantyl by environmental and physiological stress, aging, and the chronic...
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The health of the proteome depends upon protein quality control to regulate the proper synthesis, folding., translocation, and clearance of proteins. The cell is challenged constantyl by environmental and physiological stress, aging, and the chronic expressions of disease associated misfolded proteins. Substantial evidence supports the hypothesis that the expression of damaged proteins initiates a cascade of molecular events that leads to Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, Huntington's disease, and other diseases of protein conformation.
Bibliographische Angaben
- 2012, 2013, 136 Seiten, Englisch
- Herausgegeben: Richard I. Morimoto, Yves Christen
- Verlag: Springer-Verlag GmbH
- ISBN-10: 3642279287
- ISBN-13: 9783642279287
- Erscheinungsdatum: 13.12.2012
Abhängig von Bildschirmgröße und eingestellter Schriftgröße kann die Seitenzahl auf Ihrem Lesegerät variieren.
eBook Informationen
- Dateiformat: PDF
- Größe: 2.67 MB
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Sprache:
Englisch
Pressezitat
From the reviews:“This is a very good cutting edge book of scholarly import on the functioning of molecules and signal transduction in both neurodegeneration and neuroprotection. … I recommend this book highly to scientists in disease pathophysiology work.” (Joseph J. Grenier, Amazon.com, June, 2014)
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