Proteostasis and Chaperone Surveillance (PDF)

Dr. Laishram R. Singh is an Assistant Professor in the University of Delhi. He obtained his Master's Degree from Jamia Millia Islamia, New Delhi. After receiving Doctoral degree in protein Biophysics from Jamia Millia Islamia, New Delhi, Dr. Singh continued his postdoctoral research at Fox Chase cancer Center, Philadelphia (FCCC). During his Doctoral study he was engaged in investigating how small molecule compounds affect native protein structure, stability and enzymatic catalysis. At FCCC his main research interest encompasses understanding the Proteostasis and modulators of mutant proteins including, mutants of p53, cystathionine beta synthase and methyl tetrahydrofolate reductase. Currently Dr. Singh (at Delhi University) is working how the dysregulated proteostasis, which is the common hallmark of many neurodegenerative and metabolic disorders, could be reversed. Dr. Singh is a well-known enzymologist and protein biochemist. He has published more than 37 publications in many esteemed journals in the field of proteostatic regulation by small molecules and various heat shock proteins. Dr Singh is also a recipient of Elizabeth Knight Peterson Fellowship sponsored by FCCC, Philadelphia.



Tanveer A. Dar is Assistant Professor in Clinical Biochemistry, University of Kashmir, Srinagar, Jammu and Kashmir, India. He received his Masters in Biochemistry from Hamdard University, New Delhi, India in 2003 and PhD in Biosciences from Jamia Millia Islamia, New Delhi in 2009. After completing his PhD, he joined Post-doctoral fellowship with Prof. Bruce E. Bowler in University of Montana, USA. His main research area is protein structural biology and medicinal plant proteomics. He has published more than 20 research papers in reputed international journals in the field of protein folding and their stability in presence of small molecules solutes. He is a recipient of the Junior Research Fellowship and Senior Research Fellowship by CSIR, New Delhi, India. He was