Sickle Cell Anemia (PDF)
to be identified, its complex and fascinating pathophysiology is still not
fully understood. A single mutation in the beta-globin gene incurs numerous
molecular and cellular mechanisms that...
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Although sickle cell anemia was the first molecular disease
to be identified, its complex and fascinating pathophysiology is still not
fully understood. A single mutation in the beta-globin gene incurs numerous
molecular and cellular mechanisms that contribute to the plethora of symptoms
associated with the disease. Our knowledge regarding sickle cell disease
mechanisms, while still not complete, has broadened considerably over the last
decades. Sickle Cell Anemia: From Basic
Science to Clinical Practice aims to provide an update on our current
understanding of the disease's pathophysiology and use this information as a
basis to discuss its manifestations in childhood and adulthood. Current
therapies and prospects for the development of new approaches for the
management of the disease are also covered.
Nicola Conran - Research scientist at the University of Campinas, Brazil. Graduated in Biochemistry (University of Birmingham, UK); PhD, University of Nottingham, UK.
- 2016, 1st ed. 2016, 435 Seiten, Englisch
- Herausgegeben: Fernando Ferreira Costa, Nicola Conran
- Verlag: Springer-Verlag GmbH
- ISBN-10: 3319067133
- ISBN-13: 9783319067131
- Erscheinungsdatum: 29.03.2016
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- Größe: 10 MB
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