Thyroid and Heart (PDF)

Giorgio Iervasi is Director of the CNR Institute of Clinical Physiology (IFC). He received his MD from the University of Pisa. In 1998, he was named Chief of Cardiovascular Endocrine Research and the Clinical Physiology Unit, and from 2007 of the G. Monasterio Foundation, CNR, Tuscany Region. His research is focused on the cardio-endocrine metabolic area; special attentions has been devoted in the last 15-20 years to the understanding of the pathogenic role and clinical implications of mild thyroid dysfunction in cardiac disorders, particularly low T3 syndrome as a biomarker of poor prognosis and as a crucial contributing factor of disease mechanisms favouring the progression of heart failure. He is the coeditor of the first edition of Thyroid and Heart failure. In 2003, he received the "Featured Article of the Month" award from the AEHA International Society for his paper on low T3 syndrome in heart failure.

Alessandro Pingitore graduated in Medicine and Surgery, and received a PhD in Cardiovascular Physiopathology and a postdoctoral qualification in Cardiovascular Disease. He is currently a permanent scientist at the CNR Institute of Clinical Physiology. His main research fields are the assessment of cardiac function and morphology using non-invasive cardiac imaging, the relationship between thyroid hormone and the heart, and the physiological response to strenuous physical stress in normal or extreme environments.

Martin A. Gerdes is Professor of Medicine and Department Chair. In his early career he developed accurate methods to evaluate myocyte remodelling to better understand the relationship between myocyte shape and cardiac function during physiological and pathological growth of the heart. He discovered that changes in myocyte length and width correlate with changes in chamber circumference and wall thickness respectively and that the increase in chamber diameter/wall thickness ratio with progression to dilated heart failure is due to